Association between genetic variants in glutathione peroxidase 1 (GPx1) gene, GPx activity and the risk of prostate cancer

Kucukgergin C., Gokpinar M., Sanli O., Tefik T., Oktar T. M., Seckin S.

MINERVA UROLOGICA E NEFROLOGICA, cilt.63, sa.3, ss.183-190, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 63 Sayı: 3
  • Basım Tarihi: 2011
  • Dergi Adı: MINERVA UROLOGICA E NEFROLOGICA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
  • Sayfa Sayıları: ss.183-190
  • Anahtar Kelimeler: Prostate cancer, Glutathione peroxidase GPX1, Genetic diseases, inborn
  • İstanbul Üniversitesi Adresli: Evet

Özet

Aim. The Aim of this study was to investigate the association between GPx1 Pro198Leu polymorphism with the development and progression of prostate cancer (PCa) and evaluate whether smoking status and advanced age could modify this association.