CSF levels of HoxB3 and YKL-40 may predict conversion from clinically isolated syndrome to relapsing remitting multiple sclerosis.

Tamam Y., Gunes B., Akbayir E., Kizilay T., Karaaslan Z., Koral G., ...Daha Fazla

Multiple sclerosis and related disorders, cilt.48, sa.1, ss.102697, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 48 Sayı: 1
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1016/j.msard.2020.102697
  • Dergi Adı: Multiple sclerosis and related disorders
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.102697
  • Anahtar Kelimeler: Multiple sclerosis, Clinically isolated syndrome, HoxB3, YKL-40, Biomarker, CEREBROSPINAL-FLUID, SERUM YKL-40, MRI, BIOMARKERS, DISABILITY, ATTACKS, MARKERS, CHI3L1
  • İstanbul Üniversitesi Adresli: Evet

Özet

Introduction: Multiple sclerosis (MS) often initiates with an acute episode of neurological disturbance, known as clinically isolated syndrome (CIS). There is an unmet need for biomarkers that differentiate patients who will convert to MS and who will remain as CIS after the first attack.