Macrophage migration inhibitory factor (MIF) gene - 173 G > C polymorphism and its relationship to coronary artery disease and type 2 diabetes


Coban N., Erkan A. F., Ekici B., Kasit M., Unaltuna N., Vurgun E.

TURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGY, cilt.47, sa.1, ss.29-37, 2019 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 47 Sayı: 1
  • Basım Tarihi: 2019
  • Doi Numarası: 10.5543/tkda.2018.35005
  • Dergi Adı: TURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.29-37
  • Anahtar Kelimeler: Coronary artery disease, macrophage migration inhibitory factor gene, polymorphism, type 2 diabetes mellitus, AUGSBURG CASE-COHORT, GLUCOSE, ASSOCIATION, EXPRESSION, SEVERITY, INSULIN, RISK
  • İstanbul Üniversitesi Adresli: Evet

Özet

Objective: Recent studies indicate that macrophage migration inhibitory factor (MIF) is a potent proinflammatory cytokine which mediates the inflammatory process during atherosclerosis. The purpose of the study was to investigate an association between MIF gene polymorphism and type 2 diabetes mellitus (T2DM) and coronary artery disease (CAD) in the Turkish population.