LC-MS/MS monitoring for explosives residues and OGSR with diverse ionization temperatures in soil & hands: 30 minutes for extraction plus elution

ŞENER H., ANILANMERT B., Mavis M. E., Gursu G. G., Cengiz S.

ACTA CHROMATOGRAPHICA, cilt.34, sa.3, ss.304-314, 2022 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 34 Sayı: 3
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1556/1326.2021.00930
  • Dergi Adı: ACTA CHROMATOGRAPHICA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Biotechnology Research Abstracts, CAB Abstracts, Veterinary Science Database
  • Sayfa Sayıları: ss.304-314
  • Anahtar Kelimeler: fast LC-APCI-MS-MS analysis, explosive and OGSR in soil/tape-lift, gun-shot residues on hands, PYX, HNS, NTO, HND, ORGANIC GUNSHOT RESIDUES, SOLID-PHASE EXTRACTION, LIQUID-CHROMATOGRAPHY, MASS-SPECTROMETRY, MS METHOD, COLLECTION
  • İstanbul Üniversitesi Adresli: Evet

Özet

A fast LC-APCI-MS/MS screening/confirmation method was developed and validated for trace analyses of 18 analytes which are explosives and organic gun shot residues including the challenging ones with diverse ionization conditions, in soil and on hands. (+) and (-) ionization modes were used after a single-step, low-volume solvent extraction procedure developed using methanol. Tape-lifting, stub, alcohol wipes, cotton bud were compared for collecting the residues from hands of a shooter. Tapelifting and stub gave the highest recoveries and tape-lifting was chosen. Gradient elution system using ammonium chloride:methanol was developed. Whole procedure lasted approximately 30 min, was validated in both matrices, applied to real samples as post-blast residues, smokeless powder and the hands of a shooter, after shooting. Most of the recoveries were >80% and since all the precisions were <15%, quantitation was possible for all. Limit of Detection (LOD) and Limit of Quantification (LOQ) values were: 0.2 54.1 and 0.3 190.0 ngg(-1) in soil, and 0.2 132.3 and 1.1 355.0 ngg(-1) in tape-lift.