Atıf İçin Kopyala
Cappellini M. D., Viprakasit V., Taher A. T., Georgiev P., Kuo K. H. M., Coates T., ...Daha Fazla
NEW ENGLAND JOURNAL OF MEDICINE, cilt.382, sa.13, ss.1219-1231, 2020 (SCI-Expanded)
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Yayın Türü:
Makale / Tam Makale
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Cilt numarası:
382
Sayı:
13
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Basım Tarihi:
2020
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Doi Numarası:
10.1056/nejmoa1910182
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Dergi Adı:
NEW ENGLAND JOURNAL OF MEDICINE
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Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, Abstracts in Social Gerontology, AgeLine, BIOSIS, CAB Abstracts, Chemical Abstracts Core, CINAHL, Educational research abstracts (ERA), EMBASE, Food Science & Technology Abstracts, Gender Studies Database, International Pharmaceutical Abstracts, MEDLINE, MLA - Modern Language Association Database, Public Affairs Index, Veterinary Science Database
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Sayfa Sayıları:
ss.1219-1231
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İstanbul Üniversitesi Adresli:
Evet
Özet
Background Patients with transfusion-dependent beta-thalassemia need regular red-cell transfusions. Luspatercept, a recombinant fusion protein that binds to select transforming growth factor beta superfamily ligands, may enhance erythroid maturation and reduce the transfusion burden (the total number of red-cell units transfused) in such patients.