Anti-elastase, anti-urease and antioxidant activities of (3-13)-monohydroxyeicosanoic acid isomers

Sokmen B. B., Onar H. C., Yusufoglu A. S., Yanardag R.

JOURNAL OF THE SERBIAN CHEMICAL SOCIETY, cilt.77, sa.10, ss.1353-1361, 2012 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 77 Sayı: 10
  • Basım Tarihi: 2012
  • Doi Numarası: 10.2298/jsc120105042s
  • Dergi Adı: JOURNAL OF THE SERBIAN CHEMICAL SOCIETY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1353-1361
  • İstanbul Üniversitesi Adresli: Evet

Özet

A series of (3-13)-monohydroxyeicosanoic acid isomers were evaluated for their anti-elastase, anti-urease and. antioxidant activities for the first time in this study. All the test compounds exhibited anti-elastase, anti-urease and antioxidant activities. According to the obtained results, the hydroxyeicosanoic acid isomers in which the hydroxyl group is located in the middle or close to the middle of the chain showed higher anti-elastase, anti-urease and antioxidant activities than that of the other isomers. Therefore, (3-13)-monohydroxyeicosanoic acid isomers can be used in agriculture, pharmacy and cosmetic industries due to their excellent anti-elastase, anti-urease and antioxidant activities.