MTHFR C677T and A1298C Gene Polymorphisms in Human Kidney Cancer Tissues

Pence H. H., Caykara B., ALsaadoni H., Otunctemur A., Pence S.

ISTANBUL MEDICAL JOURNAL, cilt.20, sa.5, ss.408-412, 2019 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20 Sayı: 5
  • Basım Tarihi: 2019
  • Doi Numarası: 10.4274/imj.galenos.2019.88709
  • Dergi Adı: ISTANBUL MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.408-412
  • İstanbul Üniversitesi Adresli: Evet

Özet

Introduction: The potential effect of 5,10-methylenetetrahydrofolate reductase (MTHFR) on DNA methylation, DNA repair and DNA synthesis has made MTHFR a cancer-inducing gene. In this study, we aimed to evaluate C677T and A1298C gene polymorphisms in kidney cancer.