22nd International Conference on Oral and Maxillofacial Surgery, Melbourne, Avustralya, 27 - 30 Ekim 2015, cilt.44, ss.248
Background: Werner syndrome (WS) is a rare autosomal
recessive premature aging disease that affects connective tissue. It
causes atherosclerosis, arteriosclerosis, eye abnormalities, osteoporosis,
soft tissue calcification, premature thinning, graying, and
loss of hair, some types of cancers, as well as impaired tissue
healing.
Objectives: We report a 46-year-old male patient with WS
who had undergone a minor oral surgical procedure followed by
application of platelet-rich plasma (PRP) and hyperbaric oxygen
therapy (HBOT). Seven years of follow-up was uneventful.
Findings and conclusions:Aprominent feature ofWSis atrophy
and wasting of the soft tissue and muscles. Because wound
healing is delayed in WS, even in minor surgical operations some
precautions such as PRP application and HBOT are possible
options. Death, on average, is at almost 47 years, and the primary
cause is arteriosclerosis, diabetes mellitus, or cancer.
Surgeons must pay particular attention to use careful incision
and flap raising techniques, which are essential to facilitate
tension-free closure and avoid skin and mucosal necrosis.
Surgical treatment may be unpredictable, and strict follow-up is
required.