Progressive white-matter disease with primary cerebellar involvement: a separate entity?

Yalcinkaya C., Arslanoğlu İ., Islak C., Aydin A., Boltshauser E.

NEURORADIOLOGY, cilt.44, sa.9, ss.775-779, 2002 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 44 Sayı: 9
  • Basım Tarihi: 2002
  • Doi Numarası: 10.1007/s00234-002-0842-7
  • Dergi Adı: NEURORADIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.775-779
  • İstanbul Üniversitesi Adresli: Evet

Özet

Although its metabolic basis has not yet been clarified, we report a progressive white-matter disease in a Turkish girl, starting in the cerebellum and spreading to supratentorial white matter. The onset was at the age of 2.5 years with diabetes insipidus, followed by ataxia and pyramidal signs resulting in loss of walking. Aqueduct stenosis was first recognised at the age of 8 years. To our knowledge, this MRI and clinical pattern does not correspond to a recognised, well-defined white-matter disease and may indicate a separate entity.