TURKİSH JOURNAL OF VETERİNARY AND ANİMAL SCİENCES, cilt.29, ss.1067-1071, 2005 (SCI-Expanded)
Enerji kÝsÝtlÝ diyetle beslemenin gebeliÛin son d.nemindeki koyunlarda antioksidan savunma sistemi .zerine olan etkilerinin
ortaya ÝkarÝlmasÝ amacÝ ile yapÝlan alÝßmamÝzda 30 adet multiple gebelik oranÝ y.ksek SakÝz ÝrkÝ koyun kullanÝlmÝßtÝr. Gebe olan
koyunlar her bir grupta 10 hayvan olacak ßekilde iki gruba ayrÝlÝrken (grup II ve III), gebe olmayan 10 adet hayvandan da ..nc.
bir grup olußturulmußtur (grup I). Grup I, II ve IIIÕte bulunan koyunlar sÝrasÝyla 9,14 MJ ME/kg kuru madde (KM)-%10,23 Ham
protein (HP), 10,20 MJ ME/kg KM-%15,04 HP ve 8,82 MJ ME/kg KM-%14,47 HP ieren rasyonla beslenmißlerdir. T.m
koyunlardan gebeliÛin 105. ve 148. g.nlerinde kan .rnekleri toplanmÝß ve plazma Cu-Zn s.peroksid dismutaz (SOD), glutatyon
peroksidaz (GSH-Px), katalaz (CAT) aktiviteleri ve tiobarbiturik asit reaktif maddeleri (TBARS) konsantrasyonlarÝ tespit edilmißtir.
GebeliÛin 105. ve 148. g.nlerinde plazma Cu-Zn s.peroksid dismutaz ve TBARS d.zeyleri aÝsÝndan gruplar arasÝnda farklÝlÝk
bulunamamÝßtÝr. GebeliÛin 148. g.n.nde grup IIIÕ.n katalaz d.zeyinin Grup I ve IIÕden P < 0,05 d.zeyinde daha y.ksek olduÛu
belirlenmißtir. Yine 148. g.nde Grup IIIÕ.n GSH-Px d.zeyinin Grup IÕden P < 0,05 d.zeyinde daha y.ksek olduÛu saptanmÝßtÝr.
Gruplar iinde g.nler arasÝ yapÝlan kÝyaslamada ise sadece Grup IÕin GSH-Px aktivitesinin 148. g.ndeki artÝßÝnÝn 105. g.nden P <
0,05 d.zeyine daha y.ksek olduÛu belirlenmißtir. Sonu olarak, gebeliÛin sonunda plazma CAT ve GSH-Px konsantrasyonunun
y.ksek bulunmasÝnÝn nedeni yavrunun hidrojen peroksidin zararlÝ etkilerinden korunmasÝdÝr.
The aim of the study was to determine the effects of low energy diets on the enzymatic antioxidant activities of ewes in
late pregnancy. Thirty Chios ewes were used. Twenty pregnant ewes were divided into 2 groups of 10 ewes each (groups II and
III), with 10 non-pregnant ewes being separated into a third group (group I). The ewes in groups I, II and III were fed rations
containing 9.14 MJ ME/kg of dry matter (DM)-10.23% crude protein (CP), 10.20 MJ ME/kg of DM-15.04% CP, and 8.82 MJ
ME/kg of DM-14.47% CP, respectively. Plasma copper-zinc superoxide dismutase (Cu-Zn SOD), glutathione peroxidase (GSH-Px),
catalase (CAT) activities and thiobarbituric acid reactive substances (TBARS) concentrations were measured on days 105 and 148 of
pregnancy. No significant differences for Cu-Zn SOD and TBARS were detected among the groups on days 105 and 148 of
pregnancy. The catalase activities of group III were higher by P < 0.05 than those of both groups I and II on day 148 of pregnancy.
The GSH-Px activities of group III were higher than those of group I on day 148 of pregnancy (P < 0.05). In a 2-day comparison
of each group, only GSH-Px activities increased in group III (P < 0.05). It was concluded that the reason for the high plasma CAT
and GSH-Px activities at the end of pregnancy is to protect the foetus from the deleterious effects of hydrogen peroxide