The Effect of ZAP-70 Expression on Disease Progression in Early-Stage (Binet A) B-CLL Patients

URE U., Ar M. C., Baslar Z., Soysal T., Ongoren S., Gulseven M., ...Daha Fazla

TRAKYA UNIVERSITESI TIP FAKULTESI DERGISI, cilt.26, sa.4, ss.317-321, 2009 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26 Sayı: 4
  • Basım Tarihi: 2009
  • Dergi Adı: TRAKYA UNIVERSITESI TIP FAKULTESI DERGISI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.317-321
  • İstanbul Üniversitesi Adresli: Evet

Özet

Objectives: Chronic lymphocytic leukemia (CLL) is a heterogeneous disease with various clinical findings. Prognostic markers predicting the clinical outcome in early-stage CLL would play a major role in disease management. Various studies have shown that zeta-associated protein 70 (ZAP-70) provides significant prognostic information This retrospective, single-centre study evaluates the effect of ZAP-70 on disease progression in early-stage B-CLL